Which brand of metformin is best?
In recent years, with the increase in patients with diabetes, metformin has attracted much attention as a first-line antidiabetic drug. Many patients often struggle with which brand of metformin is more effective and has fewer side effects when purchasing. This article will combine the hot topics and hot content on the Internet in the past 10 days to provide you with a detailed analysis of metformin brand selection issues and provide structured data reference.
1. Brand classification of metformin

Metformin brands are mainly divided into two categories: original drugs and generic drugs. Original drugs are represented by Glucophage, produced by Merck; generic drugs include versions produced by many domestic pharmaceutical companies, such as Sino-American Huadong, Beijing Wansheng Pharmaceutical, etc. Here is a comparison of common brands:
| brand name | Manufacturer | Type | Dosage form |
|---|---|---|---|
| Glucophage | Merck | Original drug | Tablets, extended release tablets |
| Sino-US East China | East China Medicine | generic drugs | tablet |
| Wansheng Pharmaceutical | Beijing Wansheng Pharmaceutical | generic drugs | tablet |
| Dihua Tang Ding | Australia | Imported medicine | tablet |
2. Comparison of brand effects
According to recent patient feedback and clinical data, there are certain differences in the effects of different brands of metformin. The original drug Glucophage has a mature production process, high bioavailability, and stable hypoglycemic effect; while generic drugs may have slightly different effects due to different production processes and excipients. The following is user evaluation data for some brands:
| brand name | User satisfaction | Common side effects | Price range (yuan/box) |
|---|---|---|---|
| Glucophage | 90% | Gastrointestinal reactions are mild | 30-50 |
| Sino-US East China | 85% | Occasional gastrointestinal discomfort | 15-30 |
| Wansheng Pharmaceutical | 80% | Some patients reported nausea | 10-20 |
3. How to choose a brand that suits you
1.Economic conditions permit: It is recommended to choose the original drug Glucophage, whose efficacy and safety have been verified for many years.
2.Limited budget: You can choose generic drugs from well-known domestic pharmaceutical companies, such as Sino-American Huadong, whose quality is relatively stable.
3.Pay attention to side effects: If you are sensitive to gastrointestinal reactions, you can try the sustained-release tablet form, which has fewer side effects.
4.doctor advice: The final selection should be combined with the guidance of a doctor and adjusted according to individual circumstances.
4. Recent hot discussions
1.Dosage form selection: Sustained-release tablets have become a hot topic recently due to their small side effects, especially for elderly patients. 2.Domestic generic drug quality: With the advancement of consistency evaluation, the quality of some domestic drugs has become close to that of the original drugs. 3.Combination medication: The combination of metformin and SGLT-2 inhibitors has attracted much attention.
5. Things to note
1. No matter which brand you choose, you must take it according to your doctor's advice. 2. Monitor blood sugar and liver and kidney function regularly during medication. 3. Pay attention to the storage conditions of the medicine and avoid humid or high-temperature environments.
In summary, the choice of metformin brand requires comprehensive effects, side effects, price and other factors. The original drug Glucose is still the current gold standard, but domestic high-quality generic drugs are also a cost-effective choice. I hope this article can provide you with valuable reference!
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