Why are uric acid and triglycerides high?
In recent years, with changes in lifestyle and adjustments in dietary structure, high uric acid and high triglycerides have become health issues of concern to more and more people. Abnormalities in these two indicators are not only closely related to metabolic diseases, but may also cause a variety of complications. This article will combine the hot topics and hot content on the Internet in the past 10 days to provide you with a detailed analysis of the causes, hazards and countermeasures of high uric acid and triglycerides.
1. Causes and harms of high uric acid
Uric acid is the end product of purine metabolism and is normally excreted through urine. However, when uric acid is produced too much or its excretion is reduced, the concentration of uric acid in the blood will increase, causing hyperuricemia.
| Main causes of high uric acid | Possible harm |
|---|---|
| 1. Dietary factors: excessive intake of high-purine foods (such as seafood, animal offal, red meat, etc.) | 1. Gout: Urate crystals deposit in joints, causing severe pain |
| 2. Metabolic abnormalities: Purine metabolism disorder in the body | 2. Kidney stones: uric acid crystals deposited in the kidneys |
| 3. Excretion disorders: renal insufficiency leads to reduced uric acid excretion | 3. Chronic kidney disease: long-term high uric acid damages kidney function |
| 4. Genetic factors: familial hyperuricemia | 4. Cardiovascular disease: Increases the risk of hypertension and coronary heart disease |
| 5. Drug effects: certain diuretics, immunosuppressants, etc. | 5. Metabolic syndrome: closely related to obesity, diabetes, etc. |
2. Causes and harms of high triglycerides
Triglycerides are the most common type of fat in the blood and are primarily derived from dietary fat and synthesized by the liver. When triglyceride levels are too high, the risk of cardiovascular disease increases.
| Main causes of high triglycerides | Possible harm |
|---|---|
| 1. Improper diet: high-sugar, high-fat diet, excessive drinking | 1. Atherosclerosis: Increases the risk of myocardial infarction and cerebral infarction |
| 2. Obesity: especially abdominal obesity | 2. Pancreatitis: Extremely high triglycerides can induce acute pancreatitis |
| 3. Lack of exercise: sedentary lifestyle | 3. Fatty liver disease: related to metabolic-related fatty liver disease |
| 4. Genetic factors: familial hyperlipidemia | 4. Insulin resistance: Increases risk of type 2 diabetes |
| 5. Metabolic diseases: such as diabetes, hypothyroidism, etc. | 5. Metabolic syndrome: coexisting with multiple metabolic abnormalities |
3. Common characteristics of high uric acid and high triglycerides
1.are closely related to metabolic syndrome: Abnormalities in these two indicators often appear simultaneously in patients with metabolic syndrome such as obesity, hypertension, and diabetes.
2.Dietary factors are important triggers: High-purine, high-fat, and high-sugar diets will simultaneously affect uric acid and triglyceride levels.
3.Lifestyle intervention is the basic treatment: Whether uric acid or triglycerides are high, improving lifestyle is the primary treatment measure.
4. How to reduce uric acid and triglycerides
| dietary advice | lifestyle adjustments | medical intervention |
|---|---|---|
| 1. Limit high-purine foods: reduce intake of seafood and animal offal | 1. Regular exercise: at least 150 minutes of moderate-intensity exercise per week | 1. Uric acid-lowering drugs: such as allopurinol, febuxostat, etc. |
| 2. Control fat intake: reduce saturated fat and trans fat | 2. Control weight: Control BMI between 18.5-23.9 | 2. Lipid-lowering drugs: such as statins and fibrates |
| 3. Increase dietary fiber: eat more vegetables and whole grains | 3. Limit alcohol consumption: especially avoid beer | 3. Regular monitoring: review indicators every 3-6 months |
| 4. Drink more water: more than 2000ml per day to promote uric acid excretion | 4. Quit smoking: Smoking will aggravate metabolic disorders | 4. Treat primary diseases: such as diabetes, thyroid disease, etc. |
5. Recent hot research and new discoveries
1.Intestinal flora and uric acid metabolism: The latest research has found that certain intestinal flora imbalances may lead to abnormal uric acid metabolism, and probiotic intervention may become a new treatment direction.
2.Effects of intermittent fasting on blood lipids: Recent studies have shown that scientific and reasonable intermittent fasting can help reduce triglyceride levels, but it must be carried out under the guidance of a doctor.
3.Development of new uric acid-lowering drugs: Many pharmaceutical companies are developing more selective uric acid excretion promoters, which are expected to reduce the side effects of traditional drugs.
4.Lipid-lowering effects of omega-3 fatty acids: High-purity omega-3 fatty acid preparations have been proven to significantly reduce blood lipid levels in patients with hypertriglyceridemia.
6. Expert advice and summary
1.Early screening and early intervention: It is recommended that people over 30 years old should test uric acid and blood lipids once a year, and high-risk groups should increase the frequency of testing.
2.Comprehensive management: High uric acid and triglycerides often coexist, and comprehensive measures need to be taken for management.
3.personalized treatment: Develop personalized diet, exercise and medication plans based on the patient’s specific conditions.
4.long-term persistence: The improvement of metabolic abnormalities requires long-term adherence to a healthy lifestyle and cannot rely on short-term drugs.
From the above analysis, we can see that high uric acid and triglycerides are common metabolic problems among modern people and are closely related to poor lifestyle. Only through scientific diet management, regular exercise and necessary medical intervention can these indicators be effectively controlled and the occurrence of related complications prevented.
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